Vito Genovese helped destroy La Cosa Nostra in so many ways. First in 1957 with the attempted hit on Frank Costello, then the same year with the Apalachin Meeting, if he in fact was the mastermind behind it. Then when he forced Joseph Valachi to flip in 1963, who for the first time identified the entire structure of the American Mafia to the world, including all the Families and their administrations. If not for those events, we would most likely be talking about a very different LCN today. I still blame the bosses at Apalachin for running though, if not for that I really don't think that law enforcement could've done shit at that time. Unless you're on parole, they can't tell you who you can and can't meet. It was them running that caused the mass arrests and front page coverage.

As a side note, for a lowly soldier like Valachi to be able to identify the administrations of Families from all over the country tells you how interconnected they all were.