In a series of 3 or less items, only a comma is used after the first item in the list. EXAMPLE:
I BOUGHT ORANGES, APPLES AND PEACHES FOR LUNCH.
When you have more than three items in a series, commas are used after all items prior to the "and". EXAMPLE:
HER NEW OUTFIT CONSISTED OF SHOES, SKIRT, BLOUSE, AND EARRINGS.
~~ Lolly