Sorry to join the discussion so late. Rosemary was easily the most beautiful of the girls. She was, however, "slow". However, the Kennedy's tried to pass her off as normal. She became increasingly frustrated. Also, Joe was afraid that she was going to become sexually active. He sent Rose on a cruise to Europe to make sure that she would be unavailable for an extended period of time, and then he had Rosemary lobotomized and institutionalized.

Kathleen died in England when Joe was ambassador. She fell in love with a divorced Protestant, which Joe was NOT going to allow. She was with him in an airplane when in crashed.

Joe Jr. died in the war, then Bobby and Jack were assassinated.