I honestly see one route the Colombo family can now take: Completely sever all ties to Persico and his supporters and restart. I genuinely believe that the Profaci crime organization as it was once known is done.
thats what i have been preaching for quite some time now, all the persicos should be outcast and the family should start rebuilding, follow the joe massino model (before he flipped) just make close members(sons,family) of made guys already so that people will be less likely to flip cause they will be hurting their blood family as well as the crime family.