You can take their difference [or in this case, similarity] in sex organs/reproduction as a sign as they're "not meant to be" or you can take the fact that they can love each other as a sign they are meant to be. Who's to say what's "meant to be" or not? Why should we [or in this case, you and all who share your opinion] have the power so say so?
Well the main reason for sex is to reproduce. Two men and two women can have sex all they want, they’re never going to make a baby. So that’s how it’s not meant to be.
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You're ASSUMING it's not meant to be because of a inference you picked up.
I thought you said you were a Catholic? Well if you are, you sure don’t believe the teachings of Christianity.